Immunology & Inflammation Disease Area
The Immunology & Inflammation disease area is dedicated to studying the immune system's response to various stimuli and the pathological processes of inflammation. This research field aims to understand the underlying mechanisms of immune-related disorders and inflammatory diseases, paving the way for the development of innovative treatments and therapies. Utilizing advanced animal models, particularly those that closely mimic human immune responses, researchers can explore disease pathways and validate new therapeutic approaches. The integration of immunological assays, molecular biology techniques, and cutting-edge imaging technologies provides a robust platform for comprehensive immunological research.
Why Use NHP for Immunology & Inflammation Disease Modeling
NHPs share almost identical biological genes, antigens, and drug targets with humans, making them ideal for immunology research. These similarities make them highly translational models, allowing researchers to obtain reliable and applicable results.
The use of NHPs in Immunology & Inflammation disease modeling facilitates the evaluation of therapeutic efficacy and safety, leading to more accurate predictions of human responses.
Genetic Similarity
NHPs have close genetic similarities to humans, making them highly translational models for immunology research.
Immunological Similarity
NHPs share almost identical immune system components, such as antigens and drug targets, with humans, ensuring reliable results.
Therapeutic Evaluation
NHPs allow for accurate assessment of therapeutic efficacy and safety in autoimmune disease modeling, leading to better predictions of human responses.
Disease Understanding
Using NHPs facilitates a deeper understanding of autoimmune and inflammatory diseases due to their biological resemblance to humans.
Drug Development
NHPs provide applicable results in drug development, enhancing the chances of successful translation from preclinical to clinical stages.
Superior Platform for Immunology & Inflammation Research at Prisys
Prisys Biotech offers a comprehensive research platform dedicated to Immunology & Inflammation disease research. Our platform is equipped with state-of-the-art technology and methodologies, ensuring precise and reproducible results. Key features of our research platform include:
Optimized I&I NHP Model for high Repeatability
Prisys has been focusing on NHP models of I&I in terms of model development, protocol optimization, and industrial application over the past 15 years. We are the first group to validate some of the key NHP models in China such as RA, EAE, and Asthma. Our goal is to provide a comprehensive solution for I&I therapeutic research with full coverage of all relevant indications, by combining our innovative thoughts with the highly repeatable study designs.
Clinical Transformation Capabilities
To facilitate the clinical translation of your research, we offer adaptable in vivo imaging and bio-sampling plans. These capabilities allow for precise tracking of both acute and chronic immune responses, providing a comprehensive understanding of therapeutic impacts over time. This flexibility ensures that your research transitions smoothly from preclinical to clinical stages.
Advanced Immunology Assays
Our platform includes advanced immunology assays for non-human primates (NHPs), featuring detailed blood immunoglobulin (IG) profiles, immunocyte panels, and cytokine analyses. These assays are crucial for evaluating immune responses and the efficacy of immunomodulatory therapies, delivering detailed and actionable data to support your research objectives.
Immunology & Inflammation Disease Models
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1. Autoimmune Diseases:
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2. Acute & Chronic Inflammatory Diseases:
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3. Allergic Disorders:
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4. Ion channels:
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5. Transplantation and Graft Rejection:
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6. Infectious Diseases with Inflammatory Components:
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For more information on our autoimmune disease research capabilities or to discuss your specific requirements, please contact Prisys Biotech for expert support.
FAQ
What makes NHP models ideal for Immunology & Inflammation research?
NHP models closely mimic human immune responses due to their genetic and immunological similarities, making them highly translational and reliable for studying autoimmune and inflammatory diseases.
What types of diseases can be modeled using NHPs at Prisys Biotech?
Prisys Biotech specializes in models for autoimmune diseases (e.g., RA, MS), chronic inflammatory diseases (e.g., IBD, COPD), allergic disorders (e.g., atopic dermatitis), transplantation rejection, and infectious diseases with inflammatory components (e.g., sepsis).
How does Prisys Biotech support drug development in Immunology & Inflammation research?
Prisys Biotech supports various drug modalities, providing reliable preclinical data through advanced immunology assays, in vivo imaging, and bio-sampling plans, facilitating smooth clinical translation and enhancing drug development success.
What advanced technologies are used in Prisys Biotech's research platform?
Prisys Biotech employs cutting-edge immunological assays, molecular biology techniques, and imaging technologies to ensure precise, reproducible results, and comprehensive evaluation of therapeutic efficacy and safety in immunology research.