Preclinical research is a vital stage in drug development and testing, where potential drugs are evaluated for their safety, efficacy, pharmacokinetics, and pharmacodynamics before they enter clinical trials. Preclinical research requires the use of animal models that can mimic the human physiology and disease conditions as closely as possible. However, finding the right animal model is not an easy task, as different animals may have different responses to the same drug.
Prisys Biotechnology is a leading contract research organization (CRO) company that specializes in preclinical monkey experiments. Prisys Biotechnology has extensive experience and expertise in using china monkey, also known as cynomolgus monkey, as an animal model to study drug transporters, which are proteins that affect the absorption, distribution, metabolism, and excretion of drugs in the body. Drug transporters are involved in drug efficacy, safety, and interactions, and understanding their role in preclinical research is crucial for drug development and testing.
Why China Monkey?
China monkey is a type of macaque that is widely distributed in Southeast Asia and China. China monkey has many advantages as an animal model for preclinical research, such as:
China monkey has a high genetic similarity to humans, which makes it suitable for studying human diseases and drug responses.
China monkey has a well-characterized physiology and immunology, which allows for accurate measurement and analysis of drug effects and side effects.
China monkey has a relatively small body size and easy breeding, which reduces the cost and time of preclinical research.
China monkey has a diverse genetic background and environmental exposure, which reflects the variability and complexity of human populations.
How Prisys Biotechnology Uses China Monkey to Conduct Preclinical Research Efficiently and Reliably?
Prisys Biotechnology has a state-of-the-art facility that houses china monkeys that are healthy, well-cared for, and ethically sourced. Prisys Biotechnology has a team of qualified and experienced researchers who can design, conduct, analyze, and report preclinical monkey experiments according to the international standards and regulations. Prisys Biotechnology has a track record of delivering high-quality and reliable preclinical data to its clients in various fields of drug development and testing.
Here are some examples of how Prisys Biotechnology uses china monkey to conduct preclinical research efficiently and reliably:
Prisys Biotechnology collaborated with UCB Pharma to develop a unilateral ureteral obstruction model in cynomolgus monkeys, which is a model of chronic kidney disease and fibrosis. This model can be used to test potential human-specific therapeutics in kidney fibrosis, such as antibodies, proteins, and gene therapies that may not cross-react with rodent targets. By using this model, Prisys Biotechnology and UCB Pharma can obtain more relevant and accurate data for drug development and clinical translation.
Prisys Biotechnology also provides non-human primate research platform and contract research services to other biotech and pharmaceutical companies, mainly in the areas of NHP pharmacology, safety evaluation, translation research, biosafety research, and NHP resources. By using their expertise and experience in NHP models, Prisys Biotechnology can help their clients to conduct preclinical research more efficiently and reliably, as well as to comply with the ethical and regulatory standards for animal welfare and scientific quality.
Prisys Biotechnology has also published several peer-reviewed papers on NHP models of various diseases and conditions, such as liver fibrosis, lung fibrosis, renal transplantation/rejection, diabetes mellitus, and Alzheimer's disease. These publications demonstrate the scientific rigor and innovation of Prisys Biotechnology in using NHP models to advance the understanding and treatment of human diseases.
Conclusion
China monkey is an emerging animal model to study drug transporters in preclinical research. China monkey has many advantages over other animal models, such as high genetic similarity to humans, well-characterized physiology and immunology, relatively small body size and easy breeding, and diverse genetic background and environmental exposure. Prisys Biotechnology is a leading CRO company that specializes in preclinical monkey experiments using china monkey as an animal model. Prisys Biotechnology can help you conduct preclinical research efficiently and reliably using china monkey as an animal model.
If you are interested in learning more about how Prisys Biotechnology can assist you with your preclinical research needs using china monkey as an animal model, please contact us today for more information or consultation. You can also
