Biosafety Research

Name: Biosafety Research Research - Gene Therapy Biosafety Research Study - PRISYS
Brand: Prisys
SKU: 199529641

Biosafety Research Platform: Advancing Biosafety Solutions. Our ABSL-2 and BSL-2 certified labs offer comprehensive services including drug efficacy evaluation, vaccine research, clinical pulmonary tests, and more. Utilizing NHP and dog models, we accelerate new drug and gene therapy development. Learn more about our commitment to global health initiatives.

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Product Introduction

Enhanced Biosafety & Respiratory Research Capabilities in NHP

The COVID-19 pandemic underscored the critical need for robust biosafety and respiratory research capabilities, particularly in non-human primate (NHP) models. Prisys Biotech's Biosafety Research Platform is dedicated to meeting this demand by advancing scientific understanding and developing solutions in the field of biosafety.

Equipped with a registered and certified ABSL-2 laboratory, Prisys Biotech is authorized to handle specific Category II pathogenic microorganisms. This specialized facility enables us to conduct a wide range of crucial studies, including:

Drug pharmacodynamics and pharmacokinetics (PK/PD) evaluation: Assess the efficacy and safety of novel therapeutics, including antiviral and antibacterial drugs, in relevant NHP models.

Pathological and toxicological safety evaluation: Analyze the impact of potential treatments on NHP physiology and identify any potential adverse effects.

Respiratory disease modeling: Investigate the pathogenesis of respiratory infections and evaluate the efficacy of interventions in NHP models closely mimicking human respiratory systems.

Certified by the Shanghai Fengxian Health Commission, our platform allows for routine cell culture, virus strain infection (including those relevant to respiratory diseases), and in vitro experiments on various pathogenic microorganisms.

Leveraging our ABSL-2 laboratory, we offer comprehensive research services such as:

Compound activity screening: Identify promising drug candidates targeting respiratory pathogens and other infectious agents.

Vaccine efficacy evaluation: Determine the effectiveness of novel vaccine formulations in preventing or mitigating disease in NHP models.

Antibacterial drug PK/PD studies: Characterize the absorption, distribution, metabolism, and excretion of antibacterial agents in NHPs.

These services are designed to accelerate the research and development of new drugs and therapies, including AAV gene therapy, ultimately contributing to global preparedness for future pandemics and emerging infectious diseases.

Integrated Biosafety Labs for Advanced Respiratory and Infectious Disease Research

BSL-2 grade NHP vivarium:

High-Efficiency Filtered Biosafety Vivariums: Secure and controlled environments designed for high-stakes research with NHPs, ensuring optimal safety and experimental precision.
Comprehensive Species Coverage: Utilizing NHPs and dogs for their close physiological resemblance to humans, making them ideal models for infectious disease research and vaccine testing.

BSL-2 procedures:

Infection and Vaccine Research:

BSL-2 Bacterial and Virus Challenges: Conducting critical research on bacterial and viral infections, essential for understanding pathogen behavior and developing effective countermeasures.
Vaccine Challenges: Evaluating the efficacy and safety of vaccines, crucial for advancing public health initiatives.

Respiratory research units:

Clinical Pulmonary Tests:

Respirology Research: Our pressure-controlled respiratory exposure and analysis system offers human-consistent lung function tests for inhaled substances such as drugs or aerosols.
Clinical Pulmonary Tests: Including forced vital capacity, response to tracheal exposure, and response to aerosol exposure, to assess the respiratory health and reactions of subjects.

BSL-2 in vitro:

Biosample Processing and Storage:

Advanced Biosample Handling: Equipped to handle and store biosamples (cells, microorganisms, etc.) under stringent BSL-2 conditions to maintain integrity and reliability for future research. This includes secure storage, controlled culture environments, and specialized processing techniques for various biological materials.

This integrated approach provides a comprehensive and controlled environment for conducting cutting-edge research on infectious diseases, vaccine development, and respiratory health using relevant animal models and advanced in vitro techniques. Prisys Biotech's commitment to biosafety ensures the highest standards of protection for personnel, animals, and the environment while facilitating impactful scientific discoveries.

About the ABSL-2 Laboratory

Animal Biosafety Level 2 (ABSL-2) laboratories are designed to safely handle pathogenic microorganisms that can cause disease in humans or animals. These pathogens typically have low transmission risks, do not cause severe illness after laboratory exposure, and have effective treatment and preventive measures available. ABSL-2 labs are frequently utilized for infectious disease research due to their balance of safety and accessibility.

About the BSL-2 Laboratory

BSL-2 laboratories represent the second tier in biological safety levels, focusing on moderate-risk pathogens. These facilities are the most commonly used biosafety labs, providing a secure environment for conducting a wide range of research involving infectious agents.

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