Sleep Apnea/Hypopnea

BackgroundObstructive sleep apnea syndrome (OSAS) is a very common pathology with major cardiovascular, cognitive, and neurological consequences. But the pathophysiology of this disorder is still not fully understood, and there is a great need for animal models.

Model: upper airway constriction/blocking induced OSAS

Standard study duration: 12 weeks

Clinical endpoint: nocturnal polysomnography, sleeping index and time, CT

Features: The anatomies of the upper airway in monkeys has the closest similarities with humans, induced sleeping and natural sleeping analysis

Status: Open for Co-development


For more information about these models, please contact Mr. James Song,