Background: Myocardial infarction is common, in which the ischemia causes a pathological state of heart not working properly by the reduction of cardiac blood perfusion, leading to decreased heart's oxygen supply and abnormal myocardial energy metabolism.

Model: Left Anterior Descending (LAD) ischemia induced AMI

Standard study duration: 4 weeks, developed to heart failure in 6 months

Clinical endpoint: electrocardiography (ECG), AST/ALT, CK/CK-MB, CtnI, Myoglobin, LDH…

Features: Ischemia-reperfusion, permanent/transient ischemia, human similar coronary artery structure, AMI characteristic clinical ECG: QRS (Q wave) abnormality, ST segment elevation, T wave inversion, post-ischemic effects and complications (chronic heart diseases, cardio-renal syndrome, heart failure etc.)…

For more information about these models, please contact Mr. James Song, mailto:james.song@prisysbiotech.com